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Symbol Name ID |
Ctnnb1
catenin beta 1 MGI:88276 |
| Darker colors indicate more annotations |
| Human Phenotypes | Hereditary nonpolyposis colorectal carcinoma |
Adenomatous colonic polyposis |
Neoplasm of the stomach |
Nausea and vomiting |
Dysphagia |
Hepatocellular carcinoma |
| Disease(s) Associated with CTNNB1 | ||||||
| autosomal dominant intellectual developmental disorder 19 | ||||||
| colorectal cancer | ||||||
| hepatocellular carcinoma | ||||||
| medulloblastoma |
| Mouse Phenotypes | abnormal small intestinal crypt cell proliferation |
abnormal maxillary shelf morphology |
cleft secondary palate |
cleft palate |
abnormal tongue morphology |
abnormal filiform papillae morphology |
tracheoesophageal fistula |
abnormal exocrine pancreas morphology |
pancreatic acinar hypoplasia |
abnormal intestinal epithelium morphology |
abnormal crypts of Lieberkuhn morphology |
decreased Paneth cell number |
ectopic Paneth cells |
abnormal small intestine morphology |
intestine polyps |
increased intestinal adenoma incidence |
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| Availability | Mouse Genotype | ||||||||||||||||
| Ctnnb1tm1Mmt/Ctnnb1+ | |||||||||||||||||
| Ctnnb1tm1Mmt/Ctnnb1tm1Mmt Osr2tm5(cre)Jian/Osr2+ (conditional) |
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| Ctnnb1tm1Mmt/Ctnnb1tm1Mmt Shhtm1(EGFP/cre)Cjt/Shh+ (conditional) |
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| Ctnnb1tm2Kem/Ctnnb1tm2Kem Tg(Cyp1a1-cre)1Dwi/0 (conditional) |
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| Ctnnb1tm2Kem/Ctnnb1tm2Kem Tg(Tcfap2a-cre)1Will/0 (conditional) |
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| Ctnnb1tm2Kem/Ctnnb1tm2Kem Tg(KRT14-cre)#Smr/0 (conditional) |
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| Ctnnb1tm4Wbm/Ctnnb1tm4Wbm Tg(Pdx1-cre)6Tuv/0 (conditional) |
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| Bmi1tm1(cre/ERT)Mrc/Bmi1+ Ctnnb1tm1Mmt/Ctnnb1+ (conditional) |
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| Ctnnb1tm1Mmt/Ctnnb1+ Krt19tm1(cre)Mmt/Krt19+ (conditional) |
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| Ctnnb1tm1Mmt/Ctnnb1+ Tg(Fabp1-cre)1Mmt/? (conditional) |
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| Ctnnb1tm1Mmt/Ctnnb1+ Lgr5tm1(cre/ERT2)Cle/Lgr5+ (conditional) |
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| Ctnnb1tm2Kem/Ctnnb1+ Osr2tm2(cre)Jian/Osr2+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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